sage decreases effects of diazepam by pharmacodynamic antagonism. Minimal/Importance Unknown. Theoretical conversation; some species of sage might cause convulsions.
fentanyl transdermal and diazepam both of those increase sedation. Stay clear of or Use Alternate Drug. Limit use to people for whom different therapy solutions are insufficient
You may explore the several possibilities along with your health care provider. They will allow you to pick which medication is very best for yourself.
ethinylestradiol will boost the stage or outcome of diazepam by System: reducing metabolism. Use Warning/Watch. Ethinyl estradiol might inhibit the clearance of benzodiazepines that endure oxidation, thus increasing serum concentrations of concomitantly administered benzodiazepines.
cyclophosphamide will boost the level or outcome of diazepam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unfamiliar.
Utilization of benzodiazepines, such as diazepam, each utilised alone and in combination with other CNS depressants, may lead to probably deadly respiratory despair
butalbital will reduce the extent or influence of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.
Avoid or substitute An additional drug for these drugs when achievable. Assess for lack of therapeutic outcome if medication have to be coadministered. Alter dose Based on prescribing information if necessary.
stiripentol will minimize the extent or result of diazepam by affecting hepatic enzyme CYP2C19 metabolism. Modify Therapy/Monitor Closely. Look at lessening the dose of CYP2C19 substrates, if adverse reactions are knowledgeable when administered concomitantly with stiripentol.
Check Closely (1)triclabendazole will enhance the stage or result of diazepam by affecting hepatic enzyme CYP2C19 metabolism.
prednisone will lessen the extent or influence of diazepam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.
restrictions and scheduling than other benzodiazepines.48a While single actions in opposition to diazepam have
You may have existence-threatening withdrawal signs and symptoms which more info will past for several months to much more than twelve months in the event you prevent utilizing diazepam all of a sudden. Tend not to change or prevent your dose devoid of your health practitioner's assistance.
Active metabolites: N-desmethyldiazepam and temazepam, which might be the two more metabolized to oxazepam; largely removed by glucuronidation